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Post by Antony Skafi on Jul 20, 2017 7:44:48 GMT 2
Is Splenomegaly in thalassaemia related by anyway with delayed growth?
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Post by Doc on Jul 25, 2017 12:53:22 GMT 2
Splenomegaly is mostly found when the Hb is low, either because the patient has thalassaemia intermedia or because of thalassaemia major, when the pre-transfusion Hb is kept low (below 9g/dl). Low Hb is of course one of the causes delayed growth. Also splenomegaly can trap a lot of blood cells and cause a condition called hypersplenism (with increased needs for blood transfusion, low white cell and platelets)this also is accompanied by poor growth. If the patient receives blood when Hb is over 9g/dl from early childhood not only will growth be better but spleen will not enlarge and the need for removing it will not arise.
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Post by Danos on Jul 25, 2017 12:54:16 GMT 2
great
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